Sperm generally have no surface antigens
Antisperm antibodies ASA may be a reason of infertility in some individuals. They may affect pre- as well as post-fertilization stages of the reproductive process. There is ongoing progress in the identification of sperm antigens related to fertilization. The employed methods for this purpose include recombinant DNA technology and the most advanced proteomic analysis. This paper enlists the different approaches undertaken in order to identify and characterize the immunoreactive sperm antigens.
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Identification of sperm immunoreactive antigens for immunocontraceptive purposes: a review
Antisperm antibodies - Wikipedia
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Antisperm antibodies are antibodies produced against sperm antigens. ASA can be detected in ejaculate, cervical mucus, follicular fluid, and blood serum. ASA can arise whenever sperm encounter the immune system.
Infertility plagues one in six Australian couples, and in approximately half of these cases the problem lies in poor semen quality. The discovery that a man has poor semen quality can be emotionally challenging and lead to feelings of inadequacy, but should it? If we look at things from an evolutionary point of view, poor semen quality in the human male is not unexpected. All organisms are faced with a fundamental decision whether to invest limited resources into growth and survival or into reproduction. Resources used for semen production are unavailable for use elsewhere in the body.